abstract：:The emergence of the acquired immunodeficiency syndrome has wrought changes that have affected not only medicine and science, but many aspects of our social and political structures. In 1983 when it clearly became evident that acquired immunodeficiency syndrome could be transmitted by transfusions of blood components ...

journal_title：Archives of pathology & laboratory medicine

authors： Zuck TF

更新日期：1990-03-01 00:00:00

abstract：:This study was performed to evaluate the correlation between HER-2/neu gene expression and DNA ploidy patterns. Forty-five cases of breast-cancer were analyzed. Immunohistochemical staining of HER-2/neu protein on frozen sections was used to detect the HER-2/neu protein, and the Feulgen DNA staining method was used to...

journal_title：Archives of pathology & laboratory medicine

authors： Bacus SS,Bacus JW,Slamon DJ,Press MF

更新日期：1990-02-01 00:00:00

abstract：:Embolic cerebellar tissue was observed microscopically in the pulmonary and coronary arteries of a full-term male infant who died 1 hour after forceps delivery. Although embolization of brain tissue has been well documented after severe head trauma in adults and children, to our knowledge only 17 cases associated with...

journal_title：Archives of pathology & laboratory medicine

authors： Hauck AJ,Bambara JF,Edwards WD

更新日期：1990-02-01 00:00:00

abstract：:Because massive pulmonary thromboembolism is a rarely described cause of sudden and unexpected death in the pediatric age group, a 50-year retrospective review of autopsy cases at the Hospital for Sick Children, Toronto, Canada, was conducted to determine the local incidence and clinicopathologic features of such pati...

journal_title：Archives of pathology & laboratory medicine

authors： Byard RW,Cutz E

更新日期：1990-02-01 00:00:00

abstract：:We identified large histiocytes as a prominent feature in the choroid of eyes obtained at autopsy in seven of nine patients who died of leukemia. The eyes of four of the seven patients affected had leukemic choroidal infiltrates, and a majority had similar-appearing histiocytes identified in spleen or bone marrow. The...

journal_title：Archives of pathology & laboratory medicine

authors： Campbell RA,Bouldin TW,Peiffer RL

更新日期：1990-02-01 00:00:00

abstract：:Ergotamine has been associated with numerous vascular complications but only rarely with fibrosing disorders or valvular heart disease. Two patients are described in whom severe valvular dysfunction developed during ergotamine therapy for migraine headache. The surgically excised mitral and aortic valves were involved...

journal_title：Archives of pathology & laboratory medicine

authors： Hauck AJ,Edwards WD,Danielson GK,Mullany CJ,Bresnahan DR

更新日期：1990-01-01 00:00:00

abstract：:A 52-year-old man, suffering for years from malabsorption due to endemic sprue, developed progressive bowel dysfunction, ie, recurrent ileus and intestinal pseudo-obstruction. Because of partial volvulus formation, ileocecal resection was performed. Histopathologic examination of the resected specimen revealed signs o...

journal_title：Archives of pathology & laboratory medicine

authors： Ruchti C,Eisele S,Kaufmann M

更新日期：1990-01-01 00:00:00

abstract：:A case of pronounced cystic dilatation of the intrahepatic bile ducts with biliary atresia is presented. Intrahepatic biliary cysts have been described in biliary atresia, although, as far as we are aware, none as extensive as in this case. The cysts represent end-stage obstruction with irreversible liver injury; thus...

journal_title：Archives of pathology & laboratory medicine

authors： Fain JS,Lewin KJ

更新日期：1989-12-01 00:00:00

abstract：:A 35-year-old obese black American woman presented with nausea, vomiting, diarrhea, fever, cough, and chest pain of 2 weeks duration. She was pancytopenic and acidotic, with respiratory failure and hypotension. A diagnosis of septic shock was made, and the patient died 48 hours after admission. Blood cultures were pos...

journal_title：Archives of pathology & laboratory medicine

authors： Porto R,Hevia O,Hensley GT,Meyer PR

更新日期：1989-12-01 00:00:00

abstract：:Vaccination against hepatitis B is readily available and provides safe and effective immunization for individuals at increased risk for this disease. However, since the available vaccines employ a protein consisting of hepatitis B surface antigen, the question has arisen whether a detectable surface antigenemia might ...

journal_title：Archives of pathology & laboratory medicine

authors： Katkov WN,Ault MJ,Dubin SB

更新日期：1989-11-01 00:00:00

abstract：:We describe two cases of nodular fasciitis arising within the parotid glands of two patients, a 42-year-old man and a 2 1/2-year-old boy. The clinicopathologic, immunohistochemical, and ultrastructural features of this lesion and its differential diagnosis are discussed. ...

journal_title：Archives of pathology & laboratory medicine

authors： Fischer JR,Abdul-Karim FW,Robinson RA

更新日期：1989-11-01 00:00:00

abstract：:The introduction of therapeutic digoxin antibodies in the treatment of digoxin toxicity has resulted in spurious results in the many assays of cardioglycoside in serum of patients receiving this therapy. An evaluation of currently used assay methods was incorporated into a pilot Ligand Assay Survey Program of the Coll...

journal_title：Archives of pathology & laboratory medicine

authors： Hansell JR

更新日期：1989-11-01 00:00:00

abstract：:We recently reviewed a skin biopsy specimen obtained from a child with acute monocytic leukemia that demonstrated abundant mycelia present within a keratin plug of a hair follicle, a granulomatous dermal inflammatory infiltrate, and focal dermal invasion by fungi. These histologic findings were suggestive of an invasi...

journal_title：Archives of pathology & laboratory medicine

authors： Googe PB,DeCoste SD,Herold WH,Mihm MC Jr

更新日期：1989-11-01 00:00:00

abstract：:Dissecting aneurysms of the pulmonary trunk are a rare cause of sudden death. We report a case in a patient with pulmonary hypertension secondary to a patent ductus arteriosus. A brief review of the condition is also presented. ...

journal_title：Archives of pathology & laboratory medicine

authors： Nguyen GK,Dowling GP

更新日期：1989-10-01 00:00:00

abstract：:A total of 13 gastric papillary adenomas composed of 8 papillary and 5 papillotubular adenomas were examined pathologically and immunohistochemically. They showed a dome-like or pedunculated appearance and were located at the antrum, except for one adenoma. Histologically, the adenoma cells showed atypia in varying de...

journal_title：Archives of pathology & laboratory medicine

authors： Ito H,Yokozaki H,Ito M,Tahara E

更新日期：1989-09-01 00:00:00

abstract：:Alveolar proteinosis (AP) and postobstructive or endogenous lipid pneumonia (ELP) are two distinct morphologic types of phospholipid accumulation in the lung. In ELP, ultrastructurally amorphous fat accumulates in the cytoplasm of alveolar macrophages. In AP, lamellar surfactant bodies with an electron microscopic com...

journal_title：Archives of pathology & laboratory medicine

authors： Verbeken EK,Demedts M,Vanwing J,Deneffe G,Lauweryns JM

更新日期：1989-08-01 00:00:00

abstract：:A 43-year-old man with a history and symptomatology of hereditary spherocytosis underwent splenectomy and cholecystectomy for treatment of his underlying disease and of cholelithiasis. The removed gallbladder showed a serosal encapsulated nodule, supported by a short mesentery, measuring 11 x 6 x 4 mm, that histologic...

journal_title：Archives of pathology & laboratory medicine

authors： Tejada E,Danielson C

更新日期：1989-08-01 00:00:00

abstract：:Tumors of the umbilical cord, and especially angiomyxomas, are extremely unusual placental lesions. Sonography three weeks after the finding of a slightly elevated amniotic fluid alpha-fetoprotein, detected a cystic lesion of the umbilical cord in a 35-year-old woman at 19.5 weeks gestation. Two prior sonograms had be...

journal_title：Archives of pathology & laboratory medicine

authors： Yavner DL,Redline RW

更新日期：1989-08-01 00:00:00

abstract：:A 43-year-old white woman had a pheochromocytoma removed from her left adrenal gland, and one year later she developed a new left upper abdominal mass that was found to be a neuroblastoma. On both occasions, urinary vanillylmandelic acid level was elevated. However, urinary norepinephrine and epinephrine levels were i...

journal_title：Archives of pathology & laboratory medicine

authors： Amodeo C,Perez J,Sturgill BC,Turner SM,Atuk NO

更新日期：1989-07-01 00:00:00

abstract：:In 1986, the College of American Pathologists introduced an interlaboratory proficiency testing program for clinical laboratories that perform flow cytometry. Specimens consisting of fresh human lymphocytes isolated from blood or tissue or neoplastic cells grown in culture were mailed to participants by overnight mail...

journal_title：Archives of pathology & laboratory medicine

authors： Homburger HA,McCarthy R,Deodhar S

更新日期：1989-06-01 00:00:00

abstract：:Barrett's esophagus is a chronic condition in which the normal squamous mucosal lining is replaced by columnar mucosa. Campylobacter-like organism (CLOs) are implicated in the pathogenesis of gastritis and peptic ulcer disease and have been identified in Barrett's esophagus. The purpose of this study was to examine th...

journal_title：Archives of pathology & laboratory medicine

authors： Houck JA,Lucas JG

更新日期：1989-05-01 00:00:00

abstract：:Spindle cell tumors arising in the lymph nodes are very rare. We report the light microscopic, histochemical, immunohistochemical, and ultrastructural findings of an unusual solitary spindle cell tumor in a peripheral lymph node of a 45-year-old woman. Microscopically, the tumor was characterized by interlacing fascic...

journal_title：Archives of pathology & laboratory medicine

authors： Lee JY,Abell E,Shevechik GJ

更新日期：1989-05-01 00:00:00

abstract：:Assays for Chlamydia trachomatis antigen are being increasingly used in lieu of traditional cell culture methods for detection of the organism in patient specimens. While results from these assays are available considerably earlier than are those from culture, the assays have been less sensitive and specific than cult...

journal_title：Archives of pathology & laboratory medicine

authors： Kellogg JA

更新日期：1989-05-01 00:00:00

abstract：:Intestinal biopsy specimens were examined from patients with connective-tissue diseases who had symptoms that were thought to represent early gastrointestinal involvement by the disease. Specimens from the small and large intestines contained eosinophils and mast cells, in close association with Meissner's and Auerbac...

journal_title：Archives of pathology & laboratory medicine

authors： DeSchryver-Kecskemeti K,Clouse RE

更新日期：1989-04-01 00:00:00

abstract：:Blood banks and transfusion services should anticipate that patients contracting transfusion-transmitted diseases will claim that these facilities have a duty to warn or notify patients of potential transfusion risks. Although physicians treating patients must secure informed consent by describing significant risks an...

journal_title：Archives of pathology & laboratory medicine

authors： Willett DE

更新日期：1989-03-01 00:00:00

abstract：:The sophomore pathology course at the University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, Piscataway, was substantially modified with the intention of promoting guided, independent learning. The emphasis has been shifted from lectures to other modalities of instruction. This article...

journal_title：Archives of pathology & laboratory medicine

authors： Raskova J,Martin EG,Trelstad RL,Shea SM

更新日期：1989-02-01 00:00:00

abstract：:A premature male neonate, born at the 25th gestational week, developed pneumonia six days after delivery and died. Postmortem examination of the lungs revealed giant cell pneumonia with intranuclear inclusion bodies; varicella zoster infection was confirmed by immunoperoxidase stain using monoclonal antibody to varice...

journal_title：Archives of pathology & laboratory medicine

authors： Saito F,Yutani C,Imakita M,Ishibashi-Ueda H,Kanzaki T,Chiba Y

更新日期：1989-02-01 00:00:00

abstract：:Keratin and carcinoembryonic antigen immunoperoxidase staining were applied to lung cancer cells in paraffin sections of cell blocks from sputa and bronchial washings. The results correlate well with cytologic diagnosis. The large cell carcinomas are nonreactive with both antibodies. ...

journal_title：Archives of pathology & laboratory medicine

authors： Lyubsky S,Thorn R

更新日期：1989-01-01 00:00:00

abstract：:A case of nongestational, extragonadal choriocarcinoma in a middle-aged man is described. Autopsy examination confirmed that the tumor originated in the lung. The trophoblastic origin of the tumor was documented by immunoperoxidase staining for human chorionic gonadotropin. ...

journal_title：Archives of pathology & laboratory medicine

authors： Sullivan LG

更新日期：1989-01-01 00:00:00

abstract：:Fourteen cases of toxoplasmosis in subjects at autopsy with acquired immunodeficiency syndrome are reviewed. Death was related to toxoplasmosis in four cases: in three from central nervous system complications and in one case from myocarditis. In six cases the infection was identified outside of the central nervous sy...

journal_title：Archives of pathology & laboratory medicine

authors： Tschirhart D,Klatt EC

更新日期：1988-12-01 00:00:00

abstract：:To examine the role of sputum examination in the diagnosis of Pneumocystis carinii pneumonia in patients with the acquired immunodeficiency syndrome (AIDS), we conducted a prospective study of 30 patients with AIDS or suspected AIDS. Sputum was obtained just prior to bronchoscopy by spontaneous cough (20 patients) or ...

journal_title：Archives of pathology & laboratory medicine

authors： del Rio C,Guarner J,Honig EG,Slade BA

更新日期：1988-12-01 00:00:00

abstract：:We evaluated the utility of a monoclonal antibody that recognizes Pneumocystis carinii as a diagnostic tool in specimens of bronchoalveolar lavage fluid and sputum from patients in whom a diagnosis of P carinii pneumonia was being considered. In addition to routine processing for diagnosis by morphologic recognition o...

journal_title：Archives of pathology & laboratory medicine

authors： Blumenfeld W,Kovacs JA

更新日期：1988-12-01 00:00:00

abstract：:The lymph nodes from 50 axillary node dissections were evaluated by light microscopy and immunohistochemistry for the presence of dermatopathic lymphadenitis-like histologic features. On the basis of hematoxylin-eosin-stained sections alone, a histologic continuum was observed ranging from minimal paracortical changes...

journal_title：Archives of pathology & laboratory medicine

authors： Gould E,Porto R,Albores-Saavedra J,Ibe MJ

更新日期：1988-11-01 00:00:00

abstract：:kappa Light chain deposits occurring in myocardium as a complication of multiple myeloma were identified ultrastructurally and immunohistochemically in a right ventricular endomyocardial biopsy specimen from a patient who presented with clinical and hemodynamic findings of restrictive cardiomyopathy. These deposits we...

journal_title：Archives of pathology & laboratory medicine

authors： McAllister HA Jr,Seger J,Bossart M,Ferrans VJ

更新日期：1988-11-01 00:00:00

abstract：:The concept of injury as a mechanism leading to atherosclerosis has been fostered by numerous studies of initiating factors and by observation of the response of cardiovascular connective tissue, ie, cellular and extracellular matrix components. Carbohydrate-protein macromolecules of the extracellular matrix are a com...

journal_title：Archives of pathology & laboratory medicine

authors： Berenson GS,Radhakrishnamurthy B,Srinivasan SR,Vijayagopal P,Dalferes ER Jr

更新日期：1988-10-01 00:00:00

abstract：:The dramatic rise and equally dramatic fall in the mortality from coronary heart disease in the 20th century is only partly explained. This article reviews the development of our ideas concerning possible pathways other than lipids that might play a role in the development of human atherosclerosis alone or in combinat...

journal_title：Archives of pathology & laboratory medicine

authors： Benditt EP

更新日期：1988-10-01 00:00:00

abstract：:In 1986, a total of 2781 laboratories subscribed to the Comprehensive Blood Bank Survey of the College of American Pathologists (CAP) (Skokie, Ill). Performance of these laboratories on the ABO and Rh challenges was good, with 99.7% to 99.9% of the participants reporting the correct response. Antibody identification s...

journal_title：Archives of pathology & laboratory medicine

authors： Cooper ES,Polesky HF,Harrison CR,Schmidt PJ,Simon TL

更新日期：1988-09-01 00:00:00

abstract：:Values for total lactate dehydrogenase (LDH; EC 1.1.1.27) activity and LDH isoenzymes 1 and 2 were determined in 80 patients with acute myocardial infarction (AMI) and in 40 without AMI every 24 hours up to 15 days after admission, when total serum LDH level returned to normal. The sensitivity, specificity, and effici...

journal_title：Archives of pathology & laboratory medicine

authors： Rotenberg Z,Davidson E,Weinberger I,Fuchs J,Sperling O,Agmon J

更新日期：1988-09-01 00:00:00

abstract：:We feel that now, four years out, we have achieved the interim goals that we set for ourselves. There are some key aspects that we would do differently if we were now starting over, and we have provided that information to those seeking to begin similar off-site ventures who have sought our advice. There is an interes...

journal_title：Archives of pathology & laboratory medicine

authors： Matsen JM

更新日期：1988-09-01 00:00:00

abstract：:Two alpha-fucose-binding lectins, Ulex europaeus agglutinin I (UEA I) and Lotus tetragonolobus agglutinin, were employed to compare and contrast the distribution of fucosubstance in normal human kidneys and a variety of renal tumors. The study employed a total of 31 kidneys surgically removed for the presence of a var...

journal_title：Archives of pathology & laboratory medicine

authors： Hennigar RA,Sens DA,Othersen HB,Garvin AJ

更新日期：1988-09-01 00:00:00